Active Viruses Latent Proviruses and Transcriptionally Macaques in Bangladesh: Relationship of Simian Foamy Virus Infection of Rhesus
نویسندگان
چکیده
Published Ahead of Print 9 October 2013. 2013, 87(24):13628. DOI: 10.1128/JVI.01989-13. J. Virol. Matsen IV and Maxine L. Linial Hasan, Gregory A. Engel, Lisa Jones-Engel, Frederick A. Mostafa M. Feeroz, Eun-Gyung Lee, Karen L. Craig, Kamrul Khanh Soliven, Xiaoxing Wang, Christopher T. Small, Active Viruses Latent Proviruses and Transcriptionally Macaques in Bangladesh: Relationship of Simian Foamy Virus Infection of Rhesus
منابع مشابه
Simian foamy virus infection of rhesus macaques in Bangladesh: relationship of latent proviruses and transcriptionally active viruses.
Simian foamy viruses (SFV) are complex retroviruses that are ubiquitous in nonhuman primates (NHP) and are zoonotically transmitted to humans, presumably through NHP saliva, by licking, biting, and other behaviors. We have studied SFV in free-ranging rhesus macaques in Bangladesh. It has been previously shown that SFV in immunocompetent animals replicates to detectable levels only in superficia...
متن کاملReplication in a superficial epithelial cell niche explains the lack of pathogenicity of primate foamy virus infections.
Foamy viruses (FVs) are ancient retroviruses that are ubiquitous in nonhuman primates (NHPs). While FVs share many features with pathogenic retroviruses, such as human immunodeficiency virus, FV infections of their primate hosts have no apparent pathological consequences. Paradoxically, FV infections of many cell types in vitro are rapidly cytopathic. Previous work has shown that low levels of ...
متن کاملUnique Pattern of Enzootic Primate Viruses in Gibraltar Macaques
Because Gibraltar's macaques (Macaca sylvanus) have frequent contact with humans, we assayed 79 macaques for antibodies to enzootic primate viruses. All macaques were seronegative for herpesvirus B, simian T-cell lymphotropic virus, simian retrovirus, simian immunodeficiency virus, and rhesus cytomegalovirus. Seroprevalence of simian foamy virus reached 88% among adult animals.
متن کاملInfluence of Naturally Occurring Simian Foamy Viruses (SFVs) on SIV Disease Progression in the Rhesus Macaque (Macaca mulatta) Model
We have investigated the influence of naturally occurring simian foamy viruses (SFVs) on simian immunodeficiency virus (SIV) infection and disease in Indian rhesus macaques. Animals were divided into two groups based upon presence or absence of SFV; in each group, eight monkeys were injected with SIV(mac239) virus obtained from a molecular clone and four were injected with medium. Blood was col...
متن کاملTemple Monkeys and Health Implications of Commensalism, Kathmandu, Nepal
The threat of zoonotic transmission of infectious agents at monkey temples highlights the necessity of investigating the prevalence of enzootic infectious agents in these primate populations. Biological samples were collected from 39 rhesus macaques at the Swoyambhu Temple and tested by enzyme-linked immunosorbent assay, Western blot, polymerase chain reaction, or combination of these tests for...
متن کامل